Real have three days to recover from the humbling defeat before Saturday's crunch local derby against Atletico Madrid
Messi opened the scoring after two minutes and eight seconds, the quickest goal of his career, slipping the ball through Thibaut Courtois' legs from a tight angle.
LaLiga leaders Barcelona's pursuit of a 27th Spanish title gained momentum after a 2-1 comeback win over Real Madrid.
Brazil's Willian told reporters he will be doing everything he can to send his team mate Eden Hazard home early from Russia.
Lionel Messi's early goal earned Paris St Germain a 1-0 win at Olympique Lyonnais on Sunday as they opened a two-point lead at the top of Ligue 1.
Brazil coach Tite felt a terrible bitterness after they were knocked out of the World Cup by Belgium in the quarter-finals on Friday and said his side never got the breaks in an enthralling end-to-end contest.
Real Madrid endured their toughest test at Granada on Monday since La Liga restarted but showed real determination to grind out a 2-1 win and record their ninth consecutive victory as they moved within touching distance of reclaiming the title. Early goals from Ferland Mendy and Karim Benzema were enough to restore a four-point lead over Barcelona and Real will clinch their first league title since 2017 with a win over Villarreal on Thursday or at Leganes on the final day of the season.
Belgium coach Marc Wilmots, in typically self-confident mood, warned that any opponents who opened up against his team would be punished after their 1-0 win against Sweden on Wednesday.
Belgium could make wholesale changes for Saturday's European Championship clash with Ireland as they seek to keep their tournament hopes alive, coach Marc Wilmots said. "Tomorrow there will be between two and 10 changes. Only the goalkeeper is certain," he told reporters, refusing to confirm a starting place for playmaker Kevin de Bruyne, who suffered a light injury in training on Thursday.
Czech Republic goalkeeper Petr Cech ended a highly successful 11-year spell at English champions Chelsea when he moved to Premier League rivals Arsenal on Monday.
Real are on 81 points with four games to go. They are 17 points ahead of nearest rivals Sevilla.
Holders Real Madrid breezed past Chelsea into the semi-finals of the Champions League with Rodrygo's double securing a 2-0 win at Stamford Bridge.
Real Madrid barged their way back into the Spanish La Liga title race with a 3-1 victory over Atletico Madrid in a feisty derby at the Wanda Metropolitano on Saturday.
Belgium begin their campaign in St Petersburg against Russia on June 12
Zinedine Zidane has stepped down as Real Madrid coach with immediate effect five days after his team were pipped to the La Liga title by city rivals Atletico Madrid, the Spanish club said on Thursday.
With no fans allowed into venues and Real playing their home games at the 6,000-capacity Alfredo Di Stefano stadium while the Santiago Bernabeu is being refurbished, it will be a title race unlike any other.
Diego Costa scored twice but could not prevent Chelsea losing their 100 percent Premier League record in a controversial 2-2 draw at Swansea on Sunday.
Images from the UEFA Champions League group matches played on Tuesday night
Sadio Mane scored twice to help Senegal fight back and shock Brazil 4-2 in a friendly in Lisbon on Tuesday.
Raheem Sterling's stunning individual goal earned Liverpool a 1-1 draw with Chelsea in a rip-roaring League Cup semi-final first leg at Anfield on Tuesday but the dominant Merseysiders could be left to rue a missed opportunity.
Cristiano Ronaldo, Luka Modric and Mohamed Salah were named as the three finalists.
Sergio Aguero was acclaimed as "the best striker in the Premier League" by manager Manuel Pellegrini after his hat-trick helped Manchester City beat Chelsea 3-0 at Stamford Bridge on Saturday.
Thirteen-times European champions Real, who had come through each of their last three Champions League semi-final ties, had been second best for much last week's first leg which ended 1-1.
Second-half headers from Diego Godin and Raul Garcia gave holders Atletico Madrid a 2-0 win over Valencia and a place in the King's Cup quarter-finals by 3-1 on aggregate.
A summary of Saturday's action in the Euro 2024 qualifying matches.
Valencia forward Carlos Soler scored a hat-trick of penalties as his side beat La Liga champions Real Madrid 4-1 at home in an extraordinary match on Sunday.
Real Madrid through to next round, win 6-2 on aggregate, Liverpool ousted
Chelsea's Jose Mourinho, who hoped to celebrate his new contract with victory at an expectant Stamford Bridge, ended up grateful his team did not become the first Premier League champions to start their title defence with a defeat.
There was eye-catching sports action the world over and we summarise it all in this breathtaking photo feature...
Madrid were not at their best but moved three points clear of rivals Barcelona.
It was the third game in a row in which Real had broken the deadlock thanks to a penalty and they sealed the win when Benzema turned provider and allowed Marco Asensio to tap into an empty net early in the second half.
Barca feel familiar February blues as tiredness sets in
Chelsea opened up a six-point lead at the top of the Premier League despite being held to a 1-1 draw against top-four hopefuls Southampton in an absorbing game at Stamford Bridge on Sunday.
Barcelona forward Luis Suarez scored a hat-trick as his side thrashed arch-rivals Real Madrid 5-1 on Sunday in a highly entertaining 'Clasico' which surely will signal the end of hapless coach Julen Lopetegui's spell in charge of Real.
Chelsea a 1-0 win over Manchester United in a compelling Premier League clash on Sunday
Renault's Chinese test driver Guanyu Zhou won a virtual Bahrain Grand Prix on Sunday as Formula One sought to entertain fans with esports action in a season stalled by the spreading coronavirus. The first seven rounds of the real championship have been cancelled or postponed, including the showcase Monaco Grand Prix, and it remains to be seen how many there will be ultimately.
Belgium's soccer team received a hero's welcome in Brussels on Sunday, after achieving their best-ever World Cup result in Russia.
Eva Carneiro set to lose place on bench after Mourinho criticism
FA Cup winners Arsenal beat champions Chelsea 1-0 in England's Community Shield season curtain-raiser at Wembley on Sunday to end a long wait for victory over their London rivals.
Chelsea have signed Stoke City's Bosnian international goalkeeper Asmir Begovic on a four-year contract, the Premier League champions confirmed on Monday.